您只需从循环中构建一个帖子ID数组，然后从以下查询集中排除这些帖子

我不知道您的确切结构，但这里有一个非常基本的想法（需要PHP5.4+，因为数组语法很短([]), 对于旧版本，请更改回旧的数组语法(array())）

// Define the variable to hold posts 
$remove_duplicates = [];

// define and run our first query
$args1 = [
    // All your arguments for this query
];
$loop1 = new WP_Query( $args1 );
if ( $loop1->have_posts() ) {
    while ( $loop1->have_posts() ) {
    $loop1->the_post();

        // Build our array of ID\'s to exclude from other query
        $remove_duplicates[] = get_the_ID();

        // Rest of your loop

    }
    wp_reset_postdata(); // VERY VERY IMPORTANT
}

// Define our second query and exclude posts from the first
$args2 = [
    \'post__not_in\' => $remove_duplicates, // Remove posts from from $loop1
    // All your arguments for this query
];
$loop2 = new WP_Query( $args2 );
if ( $loop2->have_posts() ) {
    while ( $loop2->have_posts() ) {
    $loop2->the_post();

        // Rest of your loop

    }
    wp_reset_postdata(); // VERY VERY IMPORTANT
}